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Overview of the Models and Constraining Approaches Used in this Paper
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Overview of the Models and Constraining Approaches Used in this Paper
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Overview of the Models and Constraining Approaches Used in this Paper
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PureTech Health PLC n- palmitoylethanolamine (pea) and peroxisome proliferator activated receptor alpha (ppar- α) agonists
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Effects of <t> PPAR α </t> and PPAR γ on vessel wall, liver, adipose and muscle tissues [ <xref ref-type= 6 – 8 ]." width="250" height="auto" />
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TRICOR Systems ppar-α agonist fenofibrate
Effects of <t> PPAR α </t> and PPAR γ on vessel wall, liver, adipose and muscle tissues [ <xref ref-type= 6 – 8 ]." width="250" height="auto" />
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Sanofi dual pparα/γ agonist ave-5376
Effects of <t> PPAR α </t> and PPAR γ on vessel wall, liver, adipose and muscle tissues [ <xref ref-type= 6 – 8 ]." width="250" height="auto" />
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Effects of <t> PPAR α </t> and PPAR γ on vessel wall, liver, adipose and muscle tissues [ <xref ref-type= 6 – 8 ]." width="250" height="auto" />
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Image Search Results


Overview of the Models and Constraining Approaches Used in this Paper

Journal: Earth's Future

Article Title: Reduced Complexity Model Intercomparison Project Phase 2: Synthesizing Earth System Knowledge for Probabilistic Climate Projections

doi: 10.1029/2020EF001900

Figure Lengend Snippet: Overview of the Models and Constraining Approaches Used in this Paper

Article Snippet: FaIR‐v2.0.0‐alpha, MAGICC7, MCE‐v1‐2 and OSCARv3.1 approximately span the CMIP6 range, with FaIR‐v2.0.0‐alpha's and MCE‐v1‐2’s ranges being almost exactly in line with the CMIP6 range while MAGICC7’s projections are slightly wider than the CMIP6 range and OSCARv3.1’s projections are slightly narrower than the CMIP6 range.

Techniques: Aerosol

Promising pharmacological agents for hepatic antifibrosis in clinical trials

Journal: Journal of Clinical and Translational Hepatology

Article Title: Hepatic Antifibrotic Pharmacotherapy: Are We Approaching Success?

doi: 10.14218/JCTH.2020.00026

Figure Lengend Snippet: Promising pharmacological agents for hepatic antifibrosis in clinical trials

Article Snippet: PPAR α/δ agonist , Elafibranor , Genfit , NASH , III , RESOLVE-IT , F2-3 , 2000 , Renal impairment/failure.

Techniques: Injection

Effects of  PPAR α  and PPAR γ on vessel wall, liver, adipose and muscle tissues [ <xref ref-type= 6 – 8 ]." width="100%" height="100%">

Journal: PPAR Research

Article Title: Peroxisome Proliferator-Activated Receptor Agonists: Do They Increase Cardiovascular Risk?

doi: 10.1155/2009/460764

Figure Lengend Snippet: Effects of PPAR α and PPAR γ on vessel wall, liver, adipose and muscle tissues [ 6 8 ].

Article Snippet: PPAR α agonists increase the gene expresson of LPL and up regulate Apo A-I and A-II synthesis which are major apoproteins of the HDL fraction in the liver and resulting in increased serum HDL levels [ , ].

Techniques:

Effects of PPAR γ and  PPAR α agonists  on inflammatory mediators. Table shows the effect of PPAR γ and PPAR α receptors modulation on the expression of various inflammatory mediators. ICAM: intercellular adhesion molecule; VCAM: vascular cell adhesion molecule; IL: Interleukin; TNF- α : Tumor necrosis factor- α ; MMP-9: Matrix metalloproteinase-9; IFN: interferon; NF: Nuclear factor; iNOS: Inducible nitric oxide synthase; CRP: C-Reactive protein; CD40L: CD40 Ligand; LOX-1: low-density lipoprotein receptor-1; AP-1: Activator protein-1 [ <xref ref-type= 29 , 30 , 38 58 ]." width="100%" height="100%">

Journal: PPAR Research

Article Title: Peroxisome Proliferator-Activated Receptor Agonists: Do They Increase Cardiovascular Risk?

doi: 10.1155/2009/460764

Figure Lengend Snippet: Effects of PPAR γ and PPAR α agonists on inflammatory mediators. Table shows the effect of PPAR γ and PPAR α receptors modulation on the expression of various inflammatory mediators. ICAM: intercellular adhesion molecule; VCAM: vascular cell adhesion molecule; IL: Interleukin; TNF- α : Tumor necrosis factor- α ; MMP-9: Matrix metalloproteinase-9; IFN: interferon; NF: Nuclear factor; iNOS: Inducible nitric oxide synthase; CRP: C-Reactive protein; CD40L: CD40 Ligand; LOX-1: low-density lipoprotein receptor-1; AP-1: Activator protein-1 [ 29 , 30 , 38 58 ].

Article Snippet: PPAR α agonists increase the gene expresson of LPL and up regulate Apo A-I and A-II synthesis which are major apoproteins of the HDL fraction in the liver and resulting in increased serum HDL levels [ , ].

Techniques: Expressing